I wonder if this treatment is permanent. They’re injecting the cochlea with the crispr fluid which changes dna in the existing cells, won’t new cells have the mutated gene?
Well as I wrote this I remembered cells divide themselves to grow, so maybe the fixed gene carries over?
Yes, daughter cells of corrected ones will also have the correction applied.
That said the inner and outer hair cells (the ear cells that have “hair” strands that respond to frequency and amplitude)involved in this have extremely low if any turnover. Hair cell loss is involved in noise-related hearing loss.
I wonder if this treatment is permanent. They’re injecting the cochlea with the crispr fluid which changes dna in the existing cells, won’t new cells have the mutated gene?
Well as I wrote this I remembered cells divide themselves to grow, so maybe the fixed gene carries over?
Yes, daughter cells of corrected ones will also have the correction applied.
That said the inner and outer hair cells (the ear cells that have “hair” strands that respond to frequency and amplitude)involved in this have extremely low if any turnover. Hair cell loss is involved in noise-related hearing loss.