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Joined 1 year ago
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Cake day: June 12th, 2023




  • lemmingtoData is Beautiful@mander.xyzThe tides of Europe - Perrin RemonteEnglish
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    23 days ago
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    Why are there such high differences around Britain and pretty much nowhere else? I understand why the Mediterranean sea has almost none, such a large volume just can’t pass the Gibraltar, but I don’t understand why there is so much water moving around Britain. Is it just water moving along and being stopped by land wihnout having much other places to flow?





  • I relatively often meet 4 of these:

    • no speed limit (use the normal limit for this type of road)

    • car tires may defy laws of nature (slippery road, usually followed by a sign saying it applies during rain)

    • speed camera ahead

    • no water polluting goods (not very common, but occasionally comes up. There is also no dangerous materials with an orange trapezoid instead of an ellipse)

    I also saw don’t drive off the pier (around ferries), watch for skiers (in the mountains with cross-country skiing routes), and warning about planes, although in different design (around airports).



  • lemmingtoData is Beautiful@mander.xyzCity street network orientationEnglish
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    3 months ago
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    Also, how is the direction assigned? Especially for streets that are not straight? For example taking a beginning and end and measuring their angle wouldn’t be very representative. And how does it work with long and short streets? Are longer more heavily represented, or do they count the same? I’d like it if it took a tangent to the street every 100 m or so, but somehow I doubt that’s what they did.




  • I am by no means highly informed, but so far, I didn’t see a few things I think should be mentioned.

    Both Israel’s government and Hamas are definitely bad guys who found stirring hate towards each other a convenient way of staying in power. After all, If you have the stongest rhetoric towards someone who wants to kill people of your country, of course those people will vote for you and you can get away with things you otherwise couldn’t.

    There’s also another side which I haven’t seen explicitly mentioned and should be considered: surrounding islamic countries (who are surely not a homogeneous group). They are in a good position to help palestinian civilians, but don’t do very much for various reasons I know relatively little about.



  • There were some compatibility problems that required genetic engineering of the pig. I don’t remember specifics, but there was talk about potential dormant viruses in pig DNA that need to be removed first, possible problems with glycolsylation (sugar chains on the proteins outside of cells) and maybe more. The article also mentions that the pig had some human genes, I’m sure those help compatibility too. So many changes would be next to impossible to do until relatively recently, before use of CRISPR-Cas9. Also, it must’ve taken some time to certify the procedure. That’s why it took so much time since the topic was hot.



  • You don’t need profit in the sense of making lots of extra money compared to how much money you actually put in. I would be very interested in how much net profit is compared to gross in relative numbers. It’s a lot in absolute numbers, but I suspect not so much in relative. The problem why drug development is so very expensive is that you don’t just pay large sums for the drugs that are developed, but also for all those that are not, because they prove not useful during the testing. And there is way, way more than the successful ones, perhaps 100 to 1? I don’t have numers at hand. So in the end, you have to charge a lot of extra money above the production cost if you want to have enough money to develop any drugs at all.

    Of course, that isn’t true for old drugs. Which is a reason why generics are so much cheaper. And also why patents need to exist.

    I’m sure pharma companies abuse the system as much as they can, but not as much as it might appear at a first glance.